Epitalon
Also known as: Epithalon, Epithalone, AGAG
A tetrapeptide studied for telomerase activation and longevity.
Overview
Epitalon is a synthetic tetrapeptide based on epithalamin, a pineal gland extract. It has gained attention for its potential effects on telomerase activation and circadian rhythm regulation.
Mechanism of Action
Stimulates telomerase activity, potentially elongating telomeres. Regulates melatonin production from pineal gland. May modulate gene expression related to aging.
Pharmacokinetics
Short half-life requiring multiple daily doses or cycling protocols. Tissue distribution includes CNS.
Dosing Protocols
Note: These are research protocols from literature. This is not medical advice.
Standard Cycle
5-10 mg
Once daily
10-20 days
2-3 cycles per year
Stacking Recommendations
Peptides that may be combined based on complementary mechanisms in research settings.
Research Areas
Key Research Findings
- 1Increased telomerase activity in human somatic cells
- 2Extended lifespan in animal models
- 3Restored melatonin secretion patterns in elderly
- 4Improved retinal health in degenerative conditions
Side Effects & Contraindications
Reported Side Effects
- Generally well-tolerated
- Injection site reactions
Contraindications
- Active malignancy
- Pregnancy
Safety Considerations
Limited human data. Long-term effects unknown. Theoretical concerns about cancer if telomeres extended in malignant cells.
Storage Requirements
Store lyophilized at -20C
Scientific References
- 1