Cortagen

Also known as: Brain Peptide Bioregulator

A tetrapeptide bioregulator for cerebral cortex function.

Overview

Cortagen is a synthetic tetrapeptide designed to support cerebral cortex function. Part of the Khavinson peptide bioregulator family developed in Russia.

Mechanism of Action

Gene regulatory effects on cortical neurons. May support neurotransmitter balance and neuroplasticity. Proposed epigenetic modulation.

Pharmacokinetics

Small peptide allows oral or sublingual administration. CNS effects suggest BBB penetration.

Dosing Protocols

Note: These are research protocols from literature. This is not medical advice.

1

Oral

Dose

10-20 mg

Frequency

1-2x daily

Duration

10-30 days

Sublingual preferred

Stacking Recommendations

Peptides that may be combined based on complementary mechanisms in research settings.

Rationale: Brain support

Synergy: Cortex plus pineal function

Rationale: Cognitive

Synergy: Multiple brain peptide support

Research Areas

Cognitive FunctionBrain AgingStroke Recovery

Key Research Findings

  • 1Improved cognitive function in elderly subjects
  • 2Gene expression changes in brain tissue
  • 3Neuroprotective effects in cell culture

Side Effects & Contraindications

Reported Side Effects

  • Generally well-tolerated

Contraindications

  • Unknown

Safety Considerations

Generally well-tolerated in reported use. Limited Western data.

Storage Requirements

Store at room temperature

Scientific References

Quick Reference

Sequence
Ala-Glu-Asp-Pro
Molecular Weight
430.4 g/mol
Half-Life
Short
Bioavailability
Oral/sublingual
Research Stage
clinical phase 2
Administration
Oral, sublingual, or injection