Cerebrolysin

Also known as: FPF-1070

A peptide preparation from pig brain with neurotrophic effects.

Overview

Cerebrolysin is a peptide preparation derived from porcine brain tissue, containing low molecular weight peptides and amino acids with neurotrophic activity. Used globally for stroke and dementia.

Mechanism of Action

Contains multiple neurotrophic factors that mimic endogenous growth factors. Promotes neuroplasticity, reduces amyloid aggregation, and has anti-inflammatory effects on neurons.

Pharmacokinetics

IV or IM administration. Peptides cross BBB due to small size. Duration of effects extends beyond treatment period.

Dosing Protocols

Note: These are research protocols from literature. This is not medical advice.

1

Acute Stroke

Dose

30-50 ml

Frequency

Once daily IV

Duration

10-21 days

Diluted in saline

2

Cognitive Support

Dose

10-30 ml

Frequency

Daily IV/IM

Duration

4 weeks

May repeat courses

Stacking Recommendations

Peptides that may be combined based on complementary mechanisms in research settings.

Rationale: Neuroprotection

Synergy: Multiple neurotrophic mechanisms

Research Areas

StrokeTraumatic Brain InjuryAlzheimer's DiseaseDementia

Key Research Findings

  • 1Approved in many countries for stroke and dementia
  • 2Meta-analyses support efficacy in acute stroke
  • 3Improved cognitive function in Alzheimer's trials
  • 4Neuroprotective in TBI models

Side Effects & Contraindications

Reported Side Effects

  • Dizziness
  • Agitation
  • Injection site reactions

Contraindications

  • Epilepsy (relative)
  • Severe renal failure
  • Allergic to porcine proteins

Safety Considerations

Generally well-tolerated. Derived from animal tissue. Injection site reactions possible.

Storage Requirements

Store at 2-8C. Protect from light.

Scientific References

Quick Reference

Sequence
Mixture of brain-derived peptides
Molecular Weight
<10 kDa
Half-Life
Variable
Bioavailability
IV/IM only
Research Stage
approved
Administration
Intravenous or intramuscular