AHK-Cu
Also known as: Tripeptide-3 Copper, Alanine-Histidine-Lysine Copper
A copper tripeptide for hair growth and skin rejuvenation with growth factor activation.
Overview
AHK-Cu is a copper-binding tripeptide (Ala-His-Lys) that promotes hair follicle growth and skin health. It works synergistically with GHK-Cu and has shown particular efficacy for hair regrowth and wound healing applications.
Mechanism of Action
Binds copper ions and delivers them to tissues. Stimulates hair follicle stem cells and dermal papilla cells. Upregulates growth factors including VEGF and FGF. Enhances extracellular matrix production.
Pharmacokinetics
Topical application preferred. Copper peptides penetrate skin well. Half-life in skin ~hours.
Dosing Protocols
Note: These are research protocols from literature. This is not medical advice.
Hair Growth
1-5% solution
1-2x daily
3-6 months
Apply to scalp
Skin Rejuvenation
0.5-2% serum
1-2x daily
Ongoing
Combine with GHK-Cu
Stacking Recommendations
Peptides that may be combined based on complementary mechanisms in research settings.
Research Areas
Key Research Findings
- 1Increased hair follicle size and growth rate
- 2Enhanced dermal papilla cell proliferation
- 3Synergistic effects with GHK-Cu
- 4Improved wound closure in skin studies
Side Effects & Contraindications
Reported Side Effects
- Skin irritation (rare)
- Redness at application site
Contraindications
- Wilson's disease
- Copper sensitivity
- Open wounds (high concentration)
Safety Considerations
Generally safe topically. Avoid in Wilson's disease. May cause skin irritation in sensitive individuals.
Storage Requirements
Store at room temperature, protect from light
Scientific References
- 1