Adamax

Also known as: N-Acetyl Semax Amidate, NASA

An enhanced Semax derivative with improved stability and CNS penetration.

Overview

Adamax (N-Acetyl Semax Amidate) is a modified form of Semax with acetyl and amide modifications that enhance stability, lipophilicity, and potentially CNS penetration.

Mechanism of Action

Enhanced version of Semax mechanism. Increases BDNF/NGF, modulates dopamine and serotonin, with potentially improved delivery and duration.

Pharmacokinetics

Modifications increase stability and lipophilicity. May have improved BBB penetration and longer duration than standard Semax.

Dosing Protocols

Note: These are research protocols from literature. This is not medical advice.

1

Cognitive

Dose

150-300 mcg

Frequency

1-2x daily

Duration

2-4 weeks

Start lower than Semax doses

Stacking Recommendations

Peptides that may be combined based on complementary mechanisms in research settings.

Rationale: Enhanced nootropic stack

Synergy: Modified versions for improved effects

Research Areas

Cognitive EnhancementNeuroprotectionADHDMood

Key Research Findings

  • 1Enhanced stability compared to standard Semax
  • 2Potentially improved CNS effects
  • 3User reports suggest stronger/longer effects
  • 4Maintains BDNF-enhancing properties

Side Effects & Contraindications

Reported Side Effects

  • Stimulation
  • Nasal irritation
  • Headache

Contraindications

  • Acute psychosis
  • Pregnancy

Safety Considerations

More potent than standard Semax; start with lower doses. Similar overall safety profile.

Storage Requirements

Store at 2-8C. Protect from light.

Scientific References

Quick Reference

Sequence
Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2
Molecular Weight
855.97 g/mol
Half-Life
Extended vs standard Semax
Bioavailability
High intranasal
Research Stage
preclinical
Administration
Intranasal