Handbook/Gut & Digestive/Pentadecapeptide BPC

Pentadecapeptide BPC

Also known as: Body Protection Compound, Gastric Pentadecapeptide

The parent compound from which BPC-157 is derived, with comprehensive GI protective effects.

Overview

Pentadecapeptide BPC refers to the native body protection compound found in human gastric juice, from which BPC-157 was synthesized. This 15-amino acid peptide demonstrates broad cytoprotective effects throughout the GI tract.

Mechanism of Action

Modulates multiple protective pathways including nitric oxide system, growth factor expression, and angiogenesis. Provides comprehensive protection to GI mucosa against various insults.

Pharmacokinetics

Stable in gastric environment. Acts locally on GI mucosa with systemic effects possible at higher doses.

Dosing Protocols

Note: These are research protocols from literature. This is not medical advice.

1

GI Protection

Dose

250-500 mcg

Frequency

1-2x daily

Duration

As needed

Similar to BPC-157 protocols

Stacking Recommendations

Peptides that may be combined based on complementary mechanisms in research settings.

Rationale: Anti-inflammatory

Synergy: Protection plus inflammation control

Research Areas

GastroprotectionGI HealingUlcer PreventionMucosal DefenseGut Health

Key Research Findings

  • 1Native gastric protective peptide
  • 2Broad spectrum GI protection
  • 3Parent compound of BPC-157
  • 4Enhances mucosal defense mechanisms

Side Effects & Contraindications

Reported Side Effects

  • Generally well-tolerated

Contraindications

  • Limited data - use caution

Safety Considerations

Research compound. Based on endogenous peptide found in gastric juice. Well-tolerated in preclinical studies.

Storage Requirements

Refrigerate

Scientific References

Quick Reference

Sequence
15 amino acid sequence (BPC parent)
Molecular Weight
~1400 g/mol
Half-Life
Extended in GI tract
Bioavailability
Oral and injectable
Research Stage
preclinical
Administration
Oral or injection